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Air Pollution-Induced Oxidative Stress and Cardiovascular Toxicity: Mechanisms, Risks, and Therapeutic Strategies (en Inglés)
Gino A. Kurian (Autor)
·
Springer Nature Switzerland
· Tapa Dura
Air Pollution-Induced Oxidative Stress and Cardiovascular Toxicity: Mechanisms, Risks, and Therapeutic Strategies (en Inglés) - Gino A. Kurian
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Reseña del libro "Air Pollution-Induced Oxidative Stress and Cardiovascular Toxicity: Mechanisms, Risks, and Therapeutic Strategies (en Inglés)"
Fine particulate matter (PM₂.₅) and other air pollutants are major yet modifiable contributors to cardiovascular disease. This edited volume follows the full continuum from pollutant sources and exposure assessment to biological mechanisms, clinical outcomes, and prevention. Across 24 chapters in five sections, it examines how oxidative stress interacts with inflammation, autonomic dysregulation, endothelial and mitochondrial dysfunction, and epigenetic regulation to shape cardiovascular injury. It also asks why identical exposures do not produce identical risk. Mitochondrial functional reserve is presented as a framework for understanding when stress adaptation gives way to persistent dysfunction. Throughout, the chapters distinguish population associations, experimental findings, and clinically established benefits, giving a critical view of biomarkers, precision risk stratification, and therapeutic strategies. Written for researchers, clinicians, postgraduate students, and policymakers, the book offers an interdisciplinary foundation for understanding and reducing pollution-related cardiovascular risk.