Name: Histone Deacetylase Inhibitors (HDIs). Pharmacology, Uses & Health Effects
SKU: 64756272
Price: 93563.00 CRC
Availability: InStock
Author: Beverly D Carson
ISBN: 9781634638357

portada Histone Deacetylase Inhibitors (HDIs). Pharmacology, Uses & Health Effects

Histone Deacetylase Inhibitors (HDIs). Pharmacology, Uses & Health Effects

Formato

Libro Físico

Editorial

Nova Science Publishers

Autor

Beverly D Carson

Año

2015

N° páginas

Encuadernación

Tapa Dura

Dimensiones

28x20.8x1.3 cm

ISBN13

9781634638357

Histone Deacetylase Inhibitors (HDIs). Pharmacology, Uses & Health Effects

Beverly D Carson (Autor) · Nova Science Publishers · Tapa Dura

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Reseña del libro "Histone Deacetylase Inhibitors (HDIs). Pharmacology, Uses & Health Effects"

Histone deacetylase inhibitors (HDIs) are good anti-cancer targets. Histone acetyltransferases (HATs) and HDIs play opposite roles in the regulation of gene expression via an epigenetic mechanism. HATs catalyse the acetylation of lysine residues in histone tails, facilitating and sustaining gene transcription. HDIs remove the acetyl moieties from the epsilon-amine of lysine residues of histone tails, leading to a more condensed form of chromatin and preventing gene transcription. This book focuses on the use of HDIs for the treatment of lymphoid malignancies; myeloid malignancies; and breast cancer.